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Further, ERdj5 can also recognize and reduce non-glycoproteins (Ushioda et al., 2013) and EDEM itself is also capable of recognizing misfolded proteins through thiol-mediated interactions apart from carbohydrate binding (Lamriben et al., 2018)
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Likewise in mice, questions also remain about what cell type in liver SLC22A4 are expressed in and where ergothioneine accumulates
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