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Advanced Skin Brightening Goals 1200–1800 mg (strictly supervised) Short-term treatment cycles only Requires maintenance planning ⚠️ Doses above 1200 mg should never be self-administered

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The pre-activation of Nrf2 by electrophilic agents protects cells, partially through enhanced H 2 O 2 scavenging by the glutathione/glutathione peroxidase system, and the detoxification of reactive quinones by NAD(P)H:quinone oxidoreductase 1 [129]