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In mice, aneuploidy increased from approximately 15% to 43% with age, but SIRT2 overexpression lowered spindle defects and misalignment and increased pregnancy rates from 25% to 75% in transgenic females

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Targeted Delivery of Antioxidants via NDDS Targeted drug delivery is of great interest for selectively carrying the active pharmaceutical ingredients (APIs) to the site of action for a prolonged period at a therapeutically adequate amount