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In 5xFAD mice, loss of insulin signaling in astrocytes enhances tau phosphorylation and impairs Aβ clearance (Chen W

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For example, in a randomized double-blinded trial, NAC (600mg twice per day) given with L-arginine (1200mg per day) to diabetic men with hypertension lowered blood pressure, and improved many markers of endothelial function and inflammation, including C-reactive protein, fibrinogen, and LDL-cholesterol

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