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EGCG has been shown to activate matrix metalloproteinase (MMP)-7 (an AP-1 regulated protein) in HT-29 cells at a concentration of 25 M, however in other studies, EGCG has been shown to inhibit MMPs [49]

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The median age was 68 (range 42 to 90) years, 80% were male, and 74% were Caucasian