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However, the clinical outcomes from ACI are not always efficacious or consistent
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In cancerous cells, NF-κB is often constitutively activated, promoting the expression of pro-inflammatory cytokines such as tumor necrosis factor-alpha (TNF-α), interleukin-1β (IL-1β), and cyclooxygenase-2 (COX-2), which contribute to tumor growth and metastasis [19]
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