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To mimic the trimerized conformation of the native SARS-CoV-2 spike glycoprotein more closely, they fused naturally trimerized human resistin to the spike ectodomain to generate a stable trimer protein antigen called SmT1

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This has ben studied for the treatment of many conditions, including anemia, vitamin B6 deficiency, certain seizures in newborns, and side effects of the drug cycloserine