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Paul and Brady also note that various single-nucleotide polymorphisms (SNPs) may influence the efficacy and bioavailability, but that at this time there is neither sufficient clinical research in this area nor are tests for these SNPs commercially available
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Thus, FOXO4-DRI selectively induces apoptosis in senescent cells without adversely affecting normal cells, providing new strategies and approaches to address the accumulation of senescent cells
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