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One hallmark example is capecitabine-induced diarrhea , which results from its conversion to 5-fluorouracil (5-FU) in the gastrointestinal mucosa via thymidine phosphorylase—an enzyme that is upregulated in tumor and normal epithelial tissues

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Self-reinoculation with fecal flora changes microbiota density and composition leading to an altered bile-acid profile in the mouse small intestine (in Eng)