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In particular, the nucleus-localized Apetala2-type transcription factor, ABA-INSENSITIVE4 (ABI4), has been shown to have functions in chloroplast-to-nucleus and mitochondria-to-nucleus (retrograde) signaling pathways, and it has been suggested that ABI4 is a “master switch” for the regulation of nuclear genes in response to environmental and developmental cues (Koussevitzky et al., 2007
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