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Shiitake mushrooms that were sun-dried indoors at 26°C for 36 h exhibited reduced levels of total phenolic content (93.4 to 3.9 mg/100 g in fresh shiitake), total antioxidants (109.5 to 5.4 mg/100 g in fresh shiitake), and scavenging activity (43.2 to 6.6%) in comparison to microwave and freeze-drying techniques (98)

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The safety profile for long-term use remains unclear, and some countries have not approved it for cosmetic distribution