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However, the use of this medication requires a prolonged initial treatment period of dose-escalation to attenuate the adverse gastrointestinal effects (nausea, vomiting, diarrhea) typically associated with GLP-1R agonists, which still occurred frequently but rarely resulted in discontinuation of treatment

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There is not enough human evidence to establish: There is also no reliable, clinically established list of Dihexa side effects in humans