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Observed adverse events such as myalgia and headaches were classified as mild to moderate and assessed as unrelated to the interventions.”20 This means that researchers ultimately determined that the headaches and muscle pain experienced by patients during the studies were not due to urolithin A supplementation

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They pretreated subjects with n-acetyl-cysteine infusion (150 mg/kg) or a 5% dextrose placebo while undergoing an extended fatiguing bout of electrical stimulation of the ankle dorsiflexors