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These findings suggest that while FOXO4 is involved in the senescence pathway, it also plays a role in maintaining the viability of senescent Leydig cells by suppressing their apoptotic response, which could contribute to the accumulation of senescent cells [1]

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The article describes semaglutide as acting on GLP-1 receptors to regulate appetite, glucose homeostasis, and body weight, while glutathione is an intracellular tripeptide antioxidant that protects cells from oxidative stress