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[DOI] [PubMed] [Google Scholar] 942.Larsen BR, Assentoft M, Cotrina ML, Hua SZ, Nedergaard M, Kaila K, Voipio J, MacAulay N
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Notably, reactive astrocytes closely interact with Aβ plaques and degrade Aβ plaques in an apolipoprotein E epsilon 4 (APOE) gene-dependent manner by releasing amyloid-degrading enzymes such as insulin-degrading enzyme (IDE) and matrix metalloproteinases (MMP-2, MMP-9) 48,49
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