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FIGURE 6 3.8 Alterations of cytochromes P450 (CYP) isoforms The presence of PAHs in HnB mainstream can change the expression of the main CYPs involved in the metabolism of these species (Pavek and Dvorak, 2008)
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While N-acetylcysteine supplementation did not appear to improve overall redox state in these dogs, further research is needed to explore other antioxidant therapeutic options and their impact on longer-term outcomes [231,232]
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