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Finally, an excessive ligand density may prevent NP release from cell surfaces and impair exocytosis due to the high avidity [46]

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Understanding Fibromyalgia: A Multifaceted Condition Fibromyalgia affects roughly 4 million Americans, predominantly women, and causes symptoms such as: Chronic widespread musculoskeletal pain Severe fatigue and sleep disturbances Cognitive challenges Heightened sensitivity to touch, noise, temperature, and stress While there’s no known cure, many people find relief through a combination of lifestyle changes, stress management, and targeted nutritional support