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Figure 7 Figure 8 Discussion In the diet-induced obesity mouse model employed in this study, the animals developed body weight gain, abnormal relative organ weights, metabolic dysfunction, and liver injury

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Notably, the therapeutic efficacy of the TfR nanocarrier was more pronounced in the U87MG model compared to the GL261 model, likely due to the approximately 1.4-fold higher expression of Tf receptors in U87MG cells relative to GL261 cells