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[Google Scholar] 20.Salas-Coronas J., Vázquez-Villegas J., Lozano-Serrano A.B., Soriano-Pérez M.J., Cabeza-Barrera I., Cabezas-Fernández M.T., Villarejo-Ordóñez A., Sánchez-Sánchez J.C., Abad Vivas-Pérez J.I., Vázquez-Blanc S., Palanca-Giménez M., Cuenca-Gómez J.A

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Abbreviations Ach acetylcholine BALF broncho-alveolar lavage fluid CGRP calcitonin gene-related peptide COPD chronic obstructive pulmonary disease DOX doxycycline FDA Food and Drug Administration FEV 1 forced expiratory volume in the first second FVC forced vital capacity GSH glutathione HDAC histone deacetylase complex hPBMCs human peripheral blood mononuclear cells HRQoL health-related quality of life hs-CRP high-sensitivity C-reactive protein IFNγ interferon-gamma IL interleukin iNOS induced nitric oxide synthase IPF idiopathic pulmonary fibrosis LPS lipopolysaccharides MCHC mean corpuscular hemoglobin concentration MCP-1 monocyte chemotactic protein-1 MCV mean corpuscular volume MDA malondialdehyde MMEF maximum mid-expiratory flow MMPs matrix metalloproteinase NAC N-Acetylcysteine NFkB nuclear transcription factor NK cells natural killer cells OVA ovalbumin PaCO 2 arterial blood carbon dioxide PE pulmonary embolism PEF peak expiratory flow PFT pulmonary function tests ROS reactive oxygen species SaO 2 arterial blood oxygenation saturation SIL-BS silibinin-bis-succinat SM sulfur mustard TAT thrombin anti-thrombin TFPI tissue factor pathway inhibitor TGF-β1 transforming growth factor beta1 TNFα tumor necrosis factor-α tPA tissue plasminogen activator TR tracheal responsiveness TSM tracheal smooth muscle WBC white blood cells