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The Science of Synergy: Why This Combination Works To understand why you can take Tylenol and ibuprofen together safely, you need to look at the chemistry

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Briefly, the phosphate-buffered nitrogen-limited media contained 5 g/L yeast extract (Nucel), ammonium chloride, ammonium sulfate, magnesium sulfate, citric acid, ferrous sulfate, thiamine HCl, and standard trace metals