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[DOI] [PMC free article] [PubMed] [Google Scholar] 44.Hong YK, Hwang D-Y, Yang C-C, Cheng SM, Chen P-C, Aala W Jr., Harn HI-C, Evans ST, Onoufriadis A, Liu S-L, Lin Y-C, Chang Y-H, Lo T-K, Hung K-S, Lee Y-C, Tang M-J, Lu KQ, McGrath JA, Hsu C-K, Profibrotic subsets of SPP1 + macrophages and POSTN + fibroblasts contribute to fibrotic scarring in acne keloidalis

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In this regard, taurine can block Pink1-mediated mitophagy to maintain the number of mitochondria and inhibit glycolysis required for the polarization to M1, thus inhibiting the M1macrophages polarization