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Gene expression scope: Pickart and colleagues reported in transcriptomic analyses that GHK influences expression of more than 4,000 human genes when modeled in silico using the Connectivity Map database, including upregulation of antioxidant genes (SOD1, catalase pathway genes) and downregulation of inflammatory transcription factor NF-kB targets

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In a related experiment, HepG2 cells were incubated as described above with no prior treatment with phytochemicals