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It is very important that ghrelin has to be acylated by ghrelin O-acyl-transferase (GOAT), which binds a fatty acid side chain (C8) to serine 3 of ghrelin, forming acyl ghrelin, the active form that acts on its receptor, a G-protein-coupled receptor (GHSR-1a)
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Another 2019 review published in the International Journal of Molecular Sciences has found that resveratrol may reduce inflammation and blood clotting and may be beneficial for people with cardiovascular disease and heart failure ( 55 )
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