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7.4.3 GPx Studies highlight GPx’s substantial role, with abundant reduced thiols, in detoxifying H 2 O 2 in CF sputum, particularly when CAT is inhibited or overwhelmed (Dauletbaev et al., 2004)

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This molecular event triggers formation of multi-protein signalling complexes containing paxillin, talin, and vinculin, detectable through co-immunoprecipitation assays and proximity ligation microscopy techniques