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This process begins with the oxidation of 5-methylcytosine to 5-hydroxymethylcytosine, followed by further oxidation to 5-formylcytosine and 5-carboxylcytosine, with the oxidized intermediates eventually removed through the base excision repair mechanism, restoring the DNA to an unmethylated state
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Initial shedding commonly occurs during the first few weeks of minoxidil use
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