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This feed-forward mechanism is particularly damaging for dopaminergic neurons as their already high metabolic burden makes them unable to withstand this additional loss of GSH, resulting in apoptosis (Gabby et al., 1996)

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A randomized cross-over clinical trial [127] included 33 men and 34 women who ate four different diets each for 14 days: one that was vegetable-free (“basal”), the basal diet supplemented with either a single or double dose of crucifers, and single dose cruciferous plus apiaceous vegetables at a level that was standardized to kilogram body weight

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