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118 This investigation was prompted by results of in vivo, size-specific permeability assays, using creatinine (6-Å diameter), 4-kDa dextran (28-Å diameter), and 70-kDa dextran (120-Å diameter), that showed increased pore pathway permeability within 2 days of Citrobacter rodentium infection (Figure 4 A and B )
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