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Clinical Progress of Glutaminase Inhibitors Glutaminase inhibitors selectively target the overactive GLS in cancer cells, sparing GLS2 in normal cells: Blocking EMT (Epithelial-to-Mesenchymal Transition) : These inhibitors can help prevent EMT, which supports cancer spread
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Glutathione S-transferase mediates an ageing response to mitochondrial dysfunction [PMID: 26704446] Laboratory literature summary: Glutathione S-transferase mediates an ageing response to mitochondrial dysfunction