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Furthermore, compared to WT cells, there was a significant inhibition in IL-6 production (reduced by 70%) in C25H KO BMDMs following MDP treatment (Fig

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Consistent with this assertion, DoxyR cells also show dramatic reductions in ERK-activation and AKT-activation, as revealed by immuno-blot analysis, with phospho-specific antibody probes (Figure 7E, 7F)